So Iwata just finished up his keynote at GDC. At one point he turned it over to Reggie, and as expected, they both had a few big 3DS-related announcements, the big ones I remember were Netflix, Game Gear and Turbografix games on the 3DS VC, and a new 3D Mario game for 3DS. From what I was able to gather from my stuttering Internet connection at that point, supposedly we'll find out more about the Mario game at E3. I did see a few screenshots which will likely be on the Internet shortly (if they aren't up already).
Edit: Speak of the devil.